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KMID : 1024420130170040401
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Food Engineering Progress
2013 Volume.17 No. 4 p.401 ~ p.406
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Hepatoprotective Activity of Quality Certificated Traditional Doenjang in Korea
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Park So-Lim
Lee So-Young
Kim In-Sun
Lim Seong-Il
Song Jin
Choi Sin-Yang
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Abstract
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This study investigated the α-smooth muscle actin (α-SMA) inhibitory activity of traditional doenjang in Korea.Only the traditional doenjang of which quality was certificated in Korea was used in this study. The most significantmarker for fibrolysis is the expression of α-SMA and when MEF cells were treated with extract of Kyongbuk doen-jang, the α-SMA expression was suppressed 74%, Gangwon and Chunbuk doenjang were suppressed the α-SMAexpression more than 60% compared with the control. Particularly Kyongbuk doenjang was fermented over 2 yearsand the difference between Kyongbuk doenjang and silymarin was only 10%.
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KEYWORD
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Doenjang, hepatoprotective activity, α-smooth muscle actin inhibition
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